Extracellular E-selectin levels and its association with insulin resistance: Putative role of E-selectin as a biomarker of oxidative stress linked vascular manifestations in diabetic nephropathy
نویسندگان
چکیده
Introduction and aim: E-selectin, a cell adhesion molecule depicting nexus with oxidative stress in hyperglycemia has been documented several other clinical conditions. The present study centers around the putative role of E-selectin as biomarker diabetic nephropathy linked to stress.
 
 Materials Methods: 150 type 2 diabetics age group 35 - 50 years were classified into three groups, comprising each, based on albuminuria. Fifty healthy gender matched individuals constituted control. Extracellular Insulin quantitated appropriately. Measurement HbA1c microalbumin also enabled. Routine biochemistry analyses undertaken, established automated procedures. was initiated only following approval accorded by Institutional Ethics Committee.
 Results: levels serum significantly associated Urine Albumin-to-Creatinine Ratio (UACR) resistance light estimated Glomerular Filtration Rate.
 Conclusion: could thus act stress, observed insulin resistant diabetes.
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ژورنال
عنوان ژورنال: Biomedicine
سال: 2023
ISSN: ['2211-8020', '2211-8039']
DOI: https://doi.org/10.51248/.v43i1.2571